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23.101 Biological Concepts (Gen. Ed. Goal 7, Lab)

An approach to the study of biology that emphasizes conceptual understanding of biological systems. These areas include evolution and the origin of life, cellular processes, Mendelian and molecular genetics, ecology, behavioral science, and basic physiological systems. The interrelationship of these areas and their effect on human biology are stressed.
Laboratory. This course is not open to Biology majors.
Prerequisite: 43.095 General Mathematics or a satisfactory score on the mathematics placement exam.

23.103 Ecological Implications of Conservation (Gen. Ed. Goal 7)
An introduction to the scientific principles on which conservation should be based. Methods of conservation practice are stressed. The course includes a discussion of the development and future of the conservation movement. Occasional field trips.
No laboratory. This course is not open to Biology majors.

23.112 Biology of Marine Organisms (Gen. Ed. Goal 7)
An introduction to life in the oceans, including basic principles of ecology, a description of the important organisms, and the impact of humans on marine life. Laboratory demonstrations and occasional field trips.
No laboratory. This course is not open to Biology majors.

23.114 A Human Perspective on Genetics (Gen. Ed. Goal 7)
An exploration of the field of genetics from the rediscovery of Mendel’s work in 1900 up to the present. Once the fundamentals of the discipline are established, the emphasis is on genetics and its human ramifications. Topics include the efforts to create a DNA blueprint for humans, the prenatal diagnosis of some genetic disorders, the cloning of genes whose products are used as pharmaceuticals, and the ability to alter the genetic properties of important crop plants.

No laboratory. This course is not open to Biology majors.

23.142 Introduction to Human Biology (Gen. Ed. Goal 7, Lab)
An exploration of the functional aspects of the human body at the molecular, cellular, organ, and systems levels. Emphasis is on the development and evolution of homeostatic mechanisms that allow the body to respond and adapt to physical and emotional stresses under changing environmental conditions.
Laboratory. This course is not open to Biology or Food and Nutrition majors, except for students in the Applied Nutrition concentration.

23.160 Introduction to Organismal Biology
An introduction to the organismal, population, community, and ecosystem levels of biological organization for students intending to major in Biology. The course examines the processes of evolution, the diversity of the biological world, and the interactions of organisms and their environment. Laboratory periods concentrate on developing basic skills of observation, measuring and interpreting data, and the reading and reporting of experimental work. Offered
Fall semester only.
Note:
Students cannot receive credit for both 23.108 Biology II and 23.160 Introduction to Organismal Biology.
Prerequisite: 43.095 General Mathematics or a satisfactory score on the mathematics placement exam.

23.161 Introduction to Cell and Molecular Biology
An introduction to the molecular, cellular, and physiological levels of biological organization. The course examines the processes of energy release, photosynthesis, heredity, molecular control of cells, and selected topics in physiology. Laboratory periods concentrate on developing basic skills of observation, measuring and interpreting data, and the reading and reporting of experimental work. Offered
Spring semester only.
Note:
Students cannot receive credit for both 23.107 Biology I and
23.161 Introduction to Cell and Molecular Biology.
Prerequisite: 43.095 General Mathematics
or a satisfactory score on the mathematics placement exam.

23.200 Introduction to Environmental Science (Gen. Ed. Goal 7)
A comprehensive survey of the environmental principles concerning the interactions of humans and world resources. The role of technology in meeting the problems of growth, pollution, energy, and agriculture is examined in the context of present capabilities and the prospects for future development.

No laboratory.

23.203 Plants and Society (Gen. Ed. Goal 7)
An exploration of the dependency of humans on plants and plant products. The beginning of agriculture and its consequences for human evolution are discussed. The origins, dispersals, improvements, and uses of economically valuable plants are considered along with their relationships to the world’s economy. Occasional field trips.

No laboratory.
This course is acceptable for majors as a biology elective, but not in place of a required plant course.

23.210 Introduction to Marine Mammals
An exploration of the biology and natural history of marine mammals in the North Atlantic, including whales, dolphins, and seals. Topics include evolution, anatomy, behavior, field identification, and the history of whaling and contemporary conservation issues. Demonstration laboratory work focuses on smaller marine mammals. There is one Saturday field trip on Massachusetts Bay.

This course is not open to Biology majors.
Additional course fees apply.

Prerequisite: One college biology course. Application to campus representative of the Marine Studies Consortium must be made one semester prior to experience.

23.220 Animal Behavior
A study of the influence of natural selection on the behavior of animals. This course emphasizes the distinction between the immediate causes of behavior, including external stimuli and internal physiological mechanisms, and the ultimate consequences or survival value of behavior. Topics such as learning and instinct, aggression, territoriality, communication, and social behavior are discussed.

Laboratory.

Prerequisite: 23.160 Introduction to Organismal Biology
or 23.101 Biological Concepts or permission of the instructor.

23.232 Invertebrate Zoology
A comparative study of the invertebrate animal phyla with emphasis on marine forms. The course stresses functional morphology, development, behavior, and ecological and evolutionary relationships among the various groups. Students study live specimens whenever possible. Laboratory exercises include field trips to collect and study invertebrates of the region. Prerequisite: 23.101 Biological Concepts
or both 23.160 Introduction to Organismal Biology and 23.161 Introduction to Cell and Molecular Biology or permission of the instructor.

23.234 Comparative Vertebrate Physiology
An introduction to the functions and relationships of vertebrate organs and organ systems. The course emphasizes physiological adaptations and mechanisms by which vertebrates compensate for environmental variations.
Laboratory.
Note:
Students may receive credit for only one of the following courses: 23.234 Comparative Vertebrate Physiology, 23.272 Human Anatomy and Physiology I, or 23.333 Principles of Human Physiology.
Prerequisites: 33.107 Principles of Chemistry; 23.101 Biological Concepts
or both 23.160 Introduction to Organismal Biology and 23.161 Introduction to Cell and Molecular Biology or permission of the instructor.

23.250 Horticulture
Designed as an introduction to basic horticultural principles and practices. The course emphasizes the basic structure, growth, and development of plants, and gives the student an opportunity to develop skills in the care, propagation, and identification of horticultural plants.

No laboratory.
This course is acceptable for majors as a free elective, but not in place of a required plant course.

23.251 Vascular Plant Taxonomy
An historical view of plant classification; concepts of nomenclature, goals of phylogenetic and biosystematic investigations; anatomical and morphological characteristics important in classification; key characteristics of important temperate plant families; collection and identification techniques; and introduction to the local flora.
Laboratory.
Prerequisite: 23.101 Biological Concepts
or 23.160 Introduction to Organismal Biology.

23.252 Biology of Non-Vascular Plants
An examination of structure, life histories, physiology, taxonomy, evolution, and economics of the non-vascular plants. Special attention is given to the algae and the fungi. Laboratories, in addition to morphological studies, introduce the student to the methods of collecting, culturing and identifying these organisms.
Laboratory.
Prerequisite: 23.101 Biological Concepts
or 23.160 Introduction to Organismal Biology and 23.161 Introduction to Cell and Molecular Biology.

23.260 Cell Biology
A study of the structure and function of cells and their major organelles. Topics covered include the nucleus, mitochondria, Golgi, lysosome, endoplasmic reticulum, protein trafficking, signal transduction, cellular energetics, and gene expression. Laboratory exercises are mostly experimental.
Prerequisites: 33.107 Principles of Chemistry; 23.161 Introduction to Cell and Molecular Biology
or 23.101 Biological Concepts.

23.272 Human Anatomy and Physiology I
A study of the functional systems in the human body and the maintenance of homeostasis. Systems covered in this course include: endocrine, cardiovascular, renal (urinary), digestive and reproductive.
Laboratory. Course offered Fall semester.
Note:
Students may receive credit for only one of the following courses: 23.234 Comparative Vertebrate Physiology, 23.272 Human Anatomy and Physiology I, or 23.333 Principles of Human Physiology.
Prerequisites: 33.107 Principles of Chemistry; 23.101 Biological Concepts
or 23.161 Introduction to Cell and Molecular Biology.

23.273 Human Anatomy and Physiology II
A continuation of 23.272 Human Anatomy and Physiology I. This course focuses on tissues in the body, joints, skeletal and muscular anatomy. In addition, the nervous and respiratory systems are studied. This course is designed for students interested in pursuing a career in medical science.

Laboratory.
Course offered Spring semester.
Prerequisite: 23.272 Human Anatomy and Physiology I
or permission of instructor.

23.301 Genetics
A study of the principles governing heredity in all living things, including microorganisms, plants, and animals. Topics covered include Mendelian inheritance, molecular genetics, cytogenetics, human hereditary disease, and population genetics.

Laboratory.

Prerequisites: 23.260 Cell Biology
or permission of the instructor.

23.305 Cetacean Biology and Conservation
An examination of the biology and conservation of cetaceans: whales, dolphins, and porpoises. Topics include physiology, population biology and life history analysis, molecular genetics, morphology, distributional ecology, and social behavior. Early lectures focus on the biology of cetaceans and how they are adapted to the marine environment. Later lectures use case studies to review how biological principles can be applied to the conservation of a wide range of cetacean species.
Additional course fees apply.
Prerequisites: One year of general biology
and two upper level biology courses. Application to campus representative of the Marine Studies Consortium must be made one semester prior to experience.

23.307 Principles of Microbiology
An introduction to the structure, reproduction, physiology and taxonomy of microorganisms. Special attention is given to bacteria and viruses. Emphasis is placed on aspects of microbiology of significance to humankind, including pathogenesis, immunity, microbial ecology, pollution control, food microbiology, and biotechnology. Laboratory exercises introduce the student to standard techniques of cultivation and identification of microorganisms, food microbiology, DNA purification and analysis, immunological assays, as well as encourage independent investigations. Prerequisites: 33.107 Principles of Chemistry; 23.101 Biological Concepts
or 23.161 Introduction to Cell and Molecular Biology.

23.316 Wetlands: Hydrology, Ecology, Restoration
A study of wetlands and their role in the hydrology and ecology of global landscapes. Course topics include the function of inland and coastal marshes, swamps and bogs in water and nutrient cycles, and the role of wetlands in the support of biodiversity, from microbes to vertebrates. The biological links between wetlands and human activities, such as agriculture, coastal development, and fisheries, and the legal framework for the protection and restoration of endangered wetlands are also examined. Additional course fees apply.
Prerequisites: One year of introductory science (e.g. biology, geology, chemistry, or engineering)
and two upper level (elective) science courses. Application to campus representative of the Marine Studies Consortium must be made one semester prior to experience.

23.325 Neurobiology
An advanced examination of the development, structure and function of the central and peripheral nervous systems. Topics covered include synaptic communication, neurotransmission, sensory and motor processing, reflexes and cellular processes of learning and memory. It is designed for biology or psychology majors with an interest in neurophysiology.

Laboratory.

Prerequisite: 23.272 Human Anatomy and Physiology I
or 23.234 Comparative Vertebrate Physiology or permission of the instructor

23.333 Principles of Human Physiology
An overview of the functional anatomy of the human body and its physiology. Basic concepts concerning the skeletal, muscular, nervous, respiratory, cardiovascular, digestive, urinary, endocrine, and reproductive systems are studied.

Laboratory.
Note:
Students may receive credit for only one of the following courses: 23.234 Comparative Vertebrate Physiology, 23.272 Human Anatomy and Physiology I, or 23.333 Principles of Human Physiology.
Prerequisites: 33.107 Principles of Chemistry; 23.101 Biological Concepts
or 23.161 Introduction to Cell and Molecular Biology.

23.335 Principles of Wildlife Biology
A study of the distribution of major wildlife groups in the United States. The principles of wildlife management and evaluation of land and water habitats are stressed, as well as population growth dynamics and field procedures.
Laboratory.
Prerequisites: 33.107 Principles of Chemistry; 23.101 Biological Concepts
or 23.160 Introduction to Organismal Biology.

23.336 Ornithology
An introduction to the biology of birds, including anatomy, physiology, behavior, ecology, field identification, and conservation. Students become familiar with the techniques and tools necessary to identify bird species by sight and/or sound, as well as with basic research techniques. Laboratory includes field trips.
Prerequisite:
A biology or zoology course at the 100-level
or permission of the instructor.

23.338 Ichthyology
A study of freshwater and marine fishes with particular emphasis on those species occurring in the northeastern states.
Laboratory.
Prerequisite: 23.160 Introduction to Organismal Biology
and 23.161 Introduction to Cell and Molecular Biology or 23.101 Biological Concepts or permission of the instructor.

23.340 Immunology
A study of the principles of immunology. The immune response, antibody formation in cells and the whole animal, immuno-suppression, blood group antigens, and the kinetics of antigen-antibody reactions are described. The structure of the antibody and its active site are examined at the molecular level. The role of complement, hypersensitivity (allergy), autoallergic reactions and transplantation immunity are discussed.

Laboratory.

Prerequisite: 23.307 Principles of Microbiology
or permission of instructor.

23.341 Marine Biology
An introduction to the variety of marine environments and the biological and physical factors which contribute to the productivity of these areas. Oceanic habitats are compared to other ecosystems including tropical and temperate estuaries, coral reefs and salt marshes. Problems of human interaction with the marine environment are emphasized.
Laboratory.
Prerequisite:
23.101 Biological Concepts
or 23.160 Introduction to Organismal Biology and 23.161 Introduction to Cell and Molecular Biology.

23.348 Ecology
An advanced course that synthesizes knowledge gained in other courses and applies it to ecological problems. Emphasis is placed on the interactions between the organism and its biological and physical environments. Concepts covered include soil, climate, trophic systems, life history trade offs, behavioral ecology, biodiversity, and human impact. Laboratory includes field trips. Students may not receive credit for both 23.348 Ecology and 23.408 Ecology.
Prerequisites: 33.107 Principles of Chemistry
and two (2) biology courses (200 level or above) or permission of the instructor.

23.371 Medical Microbiology
An overview of human infectious diseases caused by viruses, bacteria, and fungi. Emphasis will be placed on current diagnostic techniques and microbial pathogenic mechanisms, and on contemporary issues that include newly emerging infectious diseases, vaccines, and bio-terrorism.
Laboratory exercises focus on state-of-the-art procedures for the isolation and identification of pathogenic microbes and for the determination of their susceptibility to chemotherapeutic drugs.
Prerequisite: 23.307 Principles of Microbiology.

23.381 Theories of Infectious Disease
An introduction to human infectious disease with emphasis on microbial pathogenic mechanisms and contemporary diagnostic techniques. Learning goals are centered on a series of case studies involving the most common infectious diseases affecting mankind.

No Laboratory.
This course cannot be used as a required Biology elective for the completion of a major in Biology.

Prerequisite: 23.307 Principles of Microbiology, an equivalent introductory course in microbiology,
or permission of the instructor.
Note
: Students cannot receive credit for both 23.371 Medical Microbiology and 23.381 Theories of Infectious Disease.

23.402 Processes of Organic Evolution
A study of the historical development of evolutionary thought in the pre- and post-Darwinian periods; the interplay among mutations, recombination, gene flow, natural selection, and genetic drift in determining the direction of evolutionary change; isolating mechanisms and the origins of species; the role of polyploidy in plant evolution; the significance of hybridization in evolution and speciation; evidences of evolution from various disciplines.
No laboratory.
Prerequisite: 23.301 Genetics.

23.406 Methods in Biological Research I
Designed to develop a working appreciation of methods of scientific inquiry through development of an original research proposal. Topics included are: problem definition, literature survey, resource bibliography, and research design, including proposed data analysis. Normally taken in the spring term of the junior year, this course is open only to Biology majors.
Prerequisite: 43.208 Biostatistics, 33.107 Principles of Chemistry,
and 33.108 Principles of Chemistry and Quantitative Analysis or equivalent, and at least four biology courses at the 200 level or above.

23.407 Methods in Biological Research II
A continuation of Methods I (23.406) in which the students implement their research design under the supervision of a department faculty member. The research may be conducted off-campus with approval of course coordinator. Open only to Biology majors.
Prerequisite: Completion of 23.406 Methods in Biological Research I with a minimum grade of C- (1.70) or better.

23.409 Developmental Biology
A study of developing organisms. Growth, regulation, differentiation and morphogenesis are considered. Emphasis is placed on molecular mechanisms.

Laboratory
exercises include both descriptive and experimental embryology.
Prerequisite: 23.301 Genetics and 33.207 Organic Chemistry I

23.411 Food Microbiology
A focus on those microorganisms involved in food production, food spoilage, and the transmission of diseases through foods. The effect of various methods of food preservation is evaluated in terms of public health, food spoilage, food quality, and nutritional value of foods.

Laboratory.

Prerequisite: 23.307 Principles of Microbiology.

23.417 Endocrinology
A study of endocrine glands, the hormones they secrete, and the effects these hormones have on their target tissues. The course examines the mechanisms of the action of hormones at the molecular, cellular, organ, and physiological levels, as well as their effects on development of the individual. Topics covered include the role of hormones in male and female reproduction, pregnancy, parturition, lactation, growth, diabetes, and exercise. In the laboratory, students perform experiments involving small animal surgery and injection of hormones.
Prerequisites: 33.107 Principles of Chemistry and one of the following biology courses: 23.234 Comparative Vertebrate Physiology, 23.272 Human Anatomy and Physiology I, 23.260 Cell Biology; or permission of the instructor.

23.435 Recombinant DNA Technology
An introduction to the principles and applications of recombinant DNA technology. Emphasis is placed on the structure, handling and manipulation of nucleic acids. A historical perspective on the emergence of recombinant DNA technology along with current topics such as transgenic organisms and human gene therapy are presented.

Laboratory
investigations include the isolation and analysis of DNA; the use of restriction endonucleases and plasmid cloning vectors; amplification of DNA; and bioinformatics.
Prerequisites: 23.260 Cell Biology
and either 23.307 Principles of Microbiology or 23.301 Genetics; or permission of the instructor.

23.451 Plant Physiology
An introduction to basic processes that regulate plant growth and development. Photosynthesis, photomorphogenesis, hormonal control, and mineral acquisition are emphasized. The laboratory has an open-ended design with an emphasis on repeatability of experimental results.
Prerequisites: 33.107 Principles of Chemistry; 23.160 Introduction to Organismal Biology
and 23.161 Introduction to Cell and Molecular Biology or 23.101 Biological Concepts.

23.456 Neighborhood Botany
Designed to acquaint the student with the tools for identifying the flowering plants and conifers in the local flora. The course will include vegetative and floral morphology, use and construction of botanical keys and collecting techniques.

23.457 Quantitative Plant Ecology
An introduction to the principles and techniques of ecology as they apply to plants in terrestrial and aquatic habitats. The course covers physiological ecology, as well as population-and community level processes. Laboratory emphasizes techniques for quantitative sampling and analysis. Occasional field trips.
Prerequisite: 23.251 Vascular Plant Taxonomy or permission of the instructor.

23.490 Independent Study in Biology
An opportunity for the Biology major to work independently in an area relevant to the student’s special interests. Each student’s experience is planned in cooperation with a department member. Progress reports and final written and oral reports are required.
Prerequisites: Biology major of junior or senior standing, two semesters completed at Framingham State College, overall QPA of 2.50, and approval of the department chair. The independent study option is reserved for those students who have previously demonstrated sufficient motivation and self-discipline to work independently.

23.496 Internship in Biology
A supervised field study in the area of the student’s interest that complements formal course work. The internship program is offered through cooperation of participating institutions that provide guidance for the interns. A minimum of 160 onsite hours is necessary to complete the internship in Biology. The 160 hours must be completed within one semester. The internship in Biology may be taken for one (1) course credit in the major as a free elective. A student may not enroll in an internship more than twice (two course credits). Any student interested in participating in an internship must consult with the Biology Department chair prior to the middle of the semester preceding the semester of the desired internship.
Prerequisites: Biology majors of senior standing, two semesters completed at Framingham State College, overall QPA of 2.50 with a 2.75 average in courses for the major, and approval of the department chair.

23.497 Internship in Biology
A supervised field study in the area of the student’s interest that complements formal course work. The internship program is offered through cooperation of participating institutions that provide guidance for the interns. A minimum of 160 onsite hours is necessary to complete the internship in Biology. The 160 hours must be completed within one semester. The internship in Biology may be taken for one (1) course credit in the major as a free elective. A student may not enroll in an internship more than twice (two course credits). Any student interested in participating in an internship must consult with the Biology Department chair prior to the middle of the semester preceding the semester of the desired internship.
Prerequisites:
Biology majors of senior standing, two semesters completed at Framingham State College, overall QPA of 2.50 with a 2.75 average in courses for the major, and approval of the department chair.

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